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Image Search Results
Journal: PLoS ONE
Article Title: Two Virus-Induced MicroRNAs Known Only from Teleost Fishes Are Orthologues of MicroRNAs Involved in Cell Cycle Control in Humans
doi: 10.1371/journal.pone.0132434
Figure Lengend Snippet: (A) Microarray analysis of miRNA regulation in liver samples from diseased rainbow trout infected with Viral hemorrhagic septicaemia virus (VHSV). The Ncode V2 probe set covering miRBase v.9 was used to detect up-(blue) and down-regulated (red) miRNAs. The miRNA probes are denoted according to the miRBase nomenclature. Organisms: dre = Danio rerio , hsa = Homo sapiens and dme = Drosophila melanogaster . (B) qPCR validation of miR-462 and miR-731 expression in the liver of VHSV-infected rainbow trout. Fold regulation was calculated from the mean values of duplicate measurements using the ΔΔC t method, using the omy-snoRNA U23 for normalization. miRNA expression was analyzed in 6 VHSV-infected fish relative to 6 uninfected fish.
Article Snippet: The microarray for detecting miRNA levels was run by a
Techniques: Microarray, Infection, Virus, Biomarker Discovery, Expressing